Thyroid stimulating hormone 0.175mIU/L is significantly low, usually indicating hyperthyroidism. It needs to be evaluated comprehensively in combination with free thyroid hormone FT3 and FT4 levels. The main influencing factors include primary hyperthyroidism, pituitary lesions, drug interference, or transient changes during pregnancy.

1. Possibility of hyperthyroidism:
Decreased thyroid stimulating hormone is most commonly seen in Graves' disease diffuse toxic goiter, which is often accompanied by symptoms such as palpitations, excessive sweating, and weight loss. Diagnosis requires testing for thyroid stimulating hormone receptor antibody TRAb and thyroid ultrasound. Treatment may include antithyroid drugs such as methimazole, radioactive iodine therapy, or surgery.
2. Pituitary abnormalities:
Pituitary dysfunction may lead to insufficient secretion of thyroid stimulating hormone, but such conditions are often accompanied by other pituitary hormone deficiency symptoms such as fatigue and hypotension. Further differentiation is required through pituitary MRI and adrenocorticotropic hormone ACTH tests.
3. Drug effects:

Long term use of glucocorticoids, dopamine drugs, or excessive thyroid hormone replacement therapy can all inhibit thyroid stimulating hormone secretion. Need to inquire in detail about medication history, adjust dosage, and recheck indicators.
4. Changes during pregnancy:
In early pregnancy, human chorionic gonadotropin (hCG) may stimulate the thyroid gland, leading to a mild decrease in thyroid stimulating hormone, which usually recovers on its own in mid pregnancy. It is necessary to judge based on gestational age and free thyroxine levels to avoid excessive intervention.
5. Subclinical hyperthyroidism:
When free thyroid hormones are normal and thyroid stimulating hormone is decreased, it is called subclinical hyperthyroidism. Elderly patients may have an increased risk of atrial fibrillation and require regular monitoring of cardiac function and bone density.

If thyroid stimulating hormone is found to be reduced, thyroid ultrasound, antibody testing, and a complete set of hormone tests should be completed. Avoid high iodine foods such as seaweed and seaweed in daily life to ensure adequate sleep. Hyperthyroidism patients need to limit caffeine intake and regularly check liver function and blood routine. If there are persistent palpitations, hand tremors, or sudden weight loss, it is recommended to seek medical attention immediately at the endocrinology department. Thyroid abnormalities during pregnancy may affect fetal development and require joint management by obstetrics and endocrinology departments.
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