Is there a problem with a high globulin of 35.5

Globulin levels of 35.5g/L are mildly elevated and are often associated with physiological factors such as chronic inflammation, immune abnormalities, or dehydration. Common causes of elevated globulin levels include chronic hepatitis, autoimmune diseases, long-term infections, dehydration, or test errors.

1. Chronic inflammation:

Long term inflammatory reactions can stimulate the immune system to produce more globulin. Common inflammations such as chronic rhinitis, gingivitis, or gastritis may lead to a slight increase in globulin, usually accompanied by an increase in C-reactive protein. This type of situation requires targeted treatment for the underlying inflammation, such as using antibiotics such as amoxicillin and metronidazole to control the infection.

2. Immune abnormalities:

Autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus can promote excessive secretion of immunoglobulin by B lymphocytes. Patients often have typical symptoms such as joint swelling and pain, rash, etc., which need to be regulated by immunosuppressants such as methotrexate and leflunomide.

3. Liver disease: In chronic hepatitis or cirrhosis, the synthesis of albumin by liver cells decreases, leading to an increase in the relative value of globulin. These patients usually have abnormal liver function, transaminase and bilirubin indicators, and require liver protection treatment and the use of antiviral drugs such as entecavir.

4. Test interference:

Blood concentration or specimen hemolysis may cause an increase in pseudoglobulin. Insufficient hydration after intense exercise and prolonged use of tourniquets during blood draws may lead to deviation in test values. It is recommended to maintain normal water intake and rest before re examination.

5. Rare causes:

Plasma cell diseases such as multiple myeloma can cause significant increases in globulin, but these diseases are usually accompanied by serious symptoms such as bone pain and anemia. When the globulin exceeds 40g/L or M protein peak appears, complete bone marrow puncture examination is required.

If mild elevation of globulin is found, test errors should be ruled out first, and blood routine and liver function should be rechecked. Daily recommendations include maintaining sufficient water intake and drinking 1500-2000ml of water daily. Moderate supplementation of vitamin C and vitamin E can help regulate immune function; Regularly conduct liver function tests and abdominal ultrasound monitoring. If there is a continuous increase or accompanied by symptoms such as weight loss and persistent fever, it is necessary to promptly screen for blood system diseases.