Is prothrombin time 15.6 severe

Prothrombin time of 15.6 seconds is considered mildly prolonged and in most cases not severe. Prolonged prothrombin time may be related to factors such as vitamin K deficiency, warfarin use, liver disease, genetic coagulation factor deficiency, disseminated intravascular coagulation, etc.

1. Vitamin K deficiency:

Vitamin K is an essential substance for the synthesis of coagulation factors II, VII, IX, and X. Insufficient intake or absorption disorders can lead to prolonged prothrombin time. Commonly seen in patients with long-term fasting and biliary obstruction. supplementing with vitamin K or adjusting diet can improve it.

2. Warfarin medication:

Warfarin, as an anticoagulant, inhibits vitamin K-dependent coagulation factor synthesis. Regular monitoring of INR values is required during medication, and doctors will adjust the dosage based on the results. Sudden bleeding or bruising requires prompt medical attention.

3. Liver disease:

The liver is the main site for the synthesis of coagulation factors. Diseases such as hepatitis and cirrhosis can lead to a decrease in the production of coagulation factors. When accompanied by symptoms such as jaundice and ascites, it is necessary to complete liver function tests and treat the primary disease accordingly.

4. Hereditary coagulation factor deficiency:

Genetic diseases such as hemophilia B can lead to the loss of specific coagulation factors. Individuals with a tendency to bleed from a young age or a family history need to undergo coagulation factor activity testing, and alternative treatment is necessary after diagnosis.

5. Diffuse intravascular coagulation:

Severe infections, malignant tumors, etc. may cause DIC, manifested as a large consumption of coagulation factors. Thrombocytopenia and fibrinogen reduction are warning signs that require urgent treatment of the underlying disease and supplementation of clotting substances.

It is necessary to observe the skin and mucous membranes for abnormal manifestations such as bruising and nosebleeds in daily life. In terms of diet, it is advisable to increase intake of foods rich in vitamin K, such as spinach and broccoli. Avoid excessive exercise that may cause trauma, and refrain from alcohol during the use of anticoagulant drugs. It is recommended to recheck coagulation function every 3-6 months. If the value continues to increase or bleeding symptoms occur, seek medical attention immediately. Special populations such as the elderly and pregnant women should strengthen monitoring frequency.