The prothrombin activity level of 130 belongs to the high range, which may indicate abnormal coagulation function or potential disease risk. The normal reference value for prothrombin activity is usually 70-120, and a value exceeding 120 requires comprehensive evaluation in conjunction with other indicators. Mild elevation of prothrombin activity may be related to recent high-fat diet, oral contraceptives, physiological changes during pregnancy, and other factors. This type of situation usually does not require special treatment, and after adjusting the diet structure, the indicators can be restored to normal after 1-2 weeks of re examination. Long term use of vitamin K supplements or certain antibiotics may also interfere with test results. It is recommended to discontinue the medication and retest. Pathological elevation of
requires vigilance against liver and gallbladder diseases such as cholestasis and early cirrhosis, which are often accompanied by symptoms such as skin yellowing and decreased appetite. Hematological diseases such as primary thrombocytosis and myeloproliferative disorders may also lead to abnormal indicators and require further examination such as bone marrow puncture for diagnosis. Some patients with malignant tumors, such as liver cancer and pancreatic cancer, may have hypercoagulation, which needs to be screened in combination with tumor markers.
It is recommended to improve coagulation function related tests such as platelet count, D-dimer, fibrinogen, etc., and avoid vigorous exercise and trauma. Reduce daily intake of high vitamin K foods such as animal organs and egg yolks, and increase water intake to promote metabolism. If the indicators continue to increase or symptoms such as subcutaneous bruising and nosebleeds appear, it is necessary to seek medical attention promptly at the hematology or hepatobiliary department.
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