Paranoia is a spectrum disorder of schizophrenia, and the severity of the condition varies from person to person. Most patients can effectively control their symptoms through standardized treatment. The treatment effect of paranoid ideation is closely related to factors such as the cause of onset, duration of illness, treatment compliance, and social support system. Patients with paranoid ideation often exhibit unfounded beliefs that they are being persecuted, which may be accompanied by anxiety, aggressive behavior, or social withdrawal. Early intervention is crucial for prognosis, and drug therapy mainly involves antipsychotic drugs such as olanzapine, risperidone, quetiapine, etc., which can regulate dopamine dysfunction in the brain. psychological therapy uses cognitive-behavioral therapy to help patients identify distorted cognition, while family therapy can improve the supportive environment. Patients with longer course of illness or concomitant mental disorders may require longer-term treatment plans. About 30% of patients have poor response to the first treatment and need to adjust medication or combine physical therapy. Difficult to treat cases can be treated with chlorpromazine or electroconvulsive therapy, but adverse reactions need to be closely monitored. The risk of recurrence is directly related to discontinuation of medication, and maintenance treatment usually takes several years. Some patients delay seeking medical treatment due to shame caused by illness, leading to chronic symptoms, making social function recovery more challenging. Maintaining a regular sleep schedule, avoiding mental stimulation, and regular follow-up visits can help stabilize the condition. Family members should learn about disease knowledge, avoid arguing with patients about delusional content, and instead guide attention to real-life evidence. The skill training provided by community rehabilitation institutions can help patients gradually return to society, and under combined treatment, more than half of patients can achieve satisfactory therapeutic effects.



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