High density lipoprotein levels of 0.81mmol/L are considered low and may increase the risk of cardiovascular disease. The main influencing factors include genetic factors, lack of exercise, obesity, poor control of diabetes, smoking, etc.

1. Genetic factors:
Some populations have insufficient synthesis of high-density lipoprotein due to genetic defects. This type of situation needs to be evaluated in conjunction with family medical history. If parents have a history of early-onset cardiovascular disease, it is recommended to improve the indicators through drug intervention. 2. Lack of exercise: Prolonged sitting can reduce lipoprotein lipase activity and affect high-density lipoprotein metabolism. Engaging in 150 minutes of aerobic exercise such as brisk walking and swimming per week can improve indicators by 0.1-0.2 mmol/L.
3. Effects of obesity:
accumulation of visceral fat accelerates the breakdown of high-density lipoprotein. For individuals with a body mass index exceeding 28, losing 5kg can increase their body mass index by 0.03-0.05mmol/L, and daily calorie intake should be controlled between 1600-1800 kcal.
4. Factors of diabetes:

Insulin resistance will inhibit the synthesis of apolipoprotein A1. When the fasting blood glucose of diabetes patients exceeds 7 mmol/L, the level of high-density lipoprotein generally decreases by 15% -20%, and the glycosylated hemoglobin should be controlled below 7% first.
5. Smoking hazards:
Cyanides in tobacco can damage the structure of high-density lipoprotein. Smoking more than 10 cigarettes per day can reduce the index by 0.1mmol/L, and after quitting smoking for 3 months, it can recover to over 80% of normal levels.
Comprehensive measures need to be taken to improve the low level of high-density lipoprotein. Increase the intake of deep-sea fish in diet, and eat salmon, sardine and other foods rich in omega -3 fatty acids 3-4 times a week; Supplement 20g of nuts such as walnuts and almonds daily; Strictly control the intake of trans fatty acids. It is recommended to use interval training mode for exercise, with 20 minute high-intensity interval exercise three times a week combined with resistance training. For patients with hypertension or diabetes, carotid ultrasound needs to be monitored regularly. When the index continues to be lower than 1.0mmol/L and accompanied by arterial plaque, nicotinic acid or statins should be used under the guidance of doctors.

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