Eosinophils at 0.03 × 10 ⁹/L belong to the low range, which may be caused by physiological or pathological factors, mainly due to long-term use of glucocorticoids, acute infections, Cushing's syndrome, stress response, bone marrow suppression, and other reasons.
1. Corticosteroid effects:
Long term use of glucocorticoids such as prednisone and dexamethasone can inhibit bone marrow hematopoietic function, leading to a decrease in eosinophils. This type of medication is commonly used to treat autoimmune diseases or allergic reactions, and regular monitoring of changes in blood routine indicators is required.
2. Acute infection state:
Bacterial or viral infection during the acute phase may trigger a stress response, manifested as a temporary decrease in eosinophils. Commonly seen in diseases such as pneumonia and urinary tract infections, it is usually accompanied by symptoms such as fever and an increase in total white blood cell count.
3. Endocrine disorders: Patients with Cushing's syndrome may inhibit eosinophil production due to excessive secretion of cortisol. These patients often have typical symptoms such as central obesity and skin purple lines, and need to be diagnosed through hormone testing. 4. Physiological stress: Intense exercise, trauma, or mental stress can stimulate adrenaline secretion, leading to a transient decrease in eosinophils. This change usually recovers on its own within 24-48 hours.
5. Bone marrow suppressive factors:
Radiation exposure, chemotherapy drugs, or aplastic anemia may damage bone marrow hematopoietic function, manifested as a decrease in whole blood cells. This type of situation requires further examination such as bone marrow puncture to confirm the diagnosis.
When low eosinophils are found, it is recommended to complete endocrine tests such as thyroid function and cortisol levels, and to re-examine blood routine to dynamically observe changes in indicators. We should pay attention to regular daily routines, avoid overwork, and ensure the intake of protein and B vitamins. For those who take hormone drugs for a long time, it is necessary to strictly follow the doctor's advice to adjust the dosage and not stop taking the medication on their own. If accompanied by persistent fatigue, repeated infections and other symptoms, it is necessary to seek medical attention promptly at the hematology department to check for hematopoietic system diseases.
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