Dapoxetine tablets usually take effect within 1-3 hours after administration, depending on individual differences, drug dosage, fasting or postprandial use, and other factors. Dapoxetine is mainly used to treat male premature ejaculation and is a short acting selective serotonin reuptake inhibitor. It should be taken 1-3 hours before sexual activity as needed. The absorption and metabolic rate of Dapoxetine tablets vary from person to person. Medication absorption is faster on an empty stomach, and may take effect about an hour earlier; Taking after meals may delay absorption and take 2-3 hours to reach the peak blood drug concentration. Patients with normal liver and kidney function have stable metabolic rates, while those with abnormal liver function may require longer periods of time. The dosage of medication can also affect the onset time, with a 30mg dose usually taking effect slightly slower than a 60mg dose. Some patients may not have significant effects when taking it for the first time and need to repeat it 2-3 times before the efficacy stabilizes.
In rare cases, delayed onset or insignificant effects may occur. The combined use of potent CYP3A4 inhibitors such as ketoconazole may prolong metabolic time. The drug clearance rate of patients with severe liver function impairment decreases by more than 50%, and the dosage should be carefully adjusted. People who are allergic to drug ingredients may experience ineffective reactions and need to stop taking the medication immediately for medical treatment. Patients who take antidepressants for a long time may have cross resistance, which affects the effectiveness of dapoxetine.
It is recommended that patients use medication in a standardized manner under the guidance of a doctor and avoid adjusting the dosage on their own. During medication, pay attention to observing physical reactions and avoid taking it with alcohol or other central nervous system inhibitors. Maintaining a regular daily routine and moderate exercise can help improve sexual function. If there is persistent ineffectiveness or adverse reactions such as palpitations and dizziness, timely follow-up should be sought. Premature ejaculation symptoms can be improved through non pharmacological methods such as pelvic floor muscle training and psychological counseling in daily life.
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