How long did sildenafil take to take effect

Sildenafil usually takes effect within 30 minutes to 1 hour after taking, depending on individual differences, dietary conditions, medication dosage, and other factors. Sildenafil is a drug used to treat male erectile dysfunction. Its mechanism of action is to inhibit the activity of phosphodiesterase 5, promote the relaxation of smooth muscle in the corpus cavernosum of the penis, increase blood flow, and thus help with erection. The onset time of medication varies from person to person. It is absorbed quickly on an empty stomach and may take about 30 minutes to take effect. If taken after meals, especially after a high-fat diet, the absorption rate of the medication may slow down and the onset time may be extended to 1 hour or longer. The dosage of medication can also affect the onset time, and higher doses may have a faster effect, but should be used under the guidance of a doctor to avoid overdose.

Some populations may have a slower response to medication, such as the elderly or those with chronic diseases, where drug metabolism is slower and the onset time may be delayed. Psychological factors such as tension and anxiety may also affect the effectiveness of medication. The effect of sildenafil usually lasts for 4 to 6 hours, during which appropriate sexual stimulation can help the drug take effect. When using, avoid taking nitrate drugs together to prevent severe hypotension.

It is recommended to use sildenafil under the guidance of a doctor and avoid adjusting the dosage on your own. During medication, pay attention to a light diet, avoid drinking alcohol and high-fat foods to improve drug absorption efficiency. Maintaining a relaxed mindset and combining it with appropriate sexual stimulation can help medication work better. If adverse reactions such as headache, facial flushing, and indigestion occur, timely consultation should be sought. Long term use should be regularly evaluated for effectiveness and safety to avoid dependence.