The occurrence of depression is closely related to psychological factors, mainly influenced by genetic susceptibility, early traumatic experiences, negative cognitive patterns, poor long-term stress coping, and personality traits.

1. Genetic susceptibility
Some individuals may be more sensitive to depression due to genetic factors. This susceptibility does not directly lead to depression, but increases the risk of developing the disease under psychological stress. People with a family history of depression may have a more intense response to stress in their brain neurotransmitter system. For such situations, the key lies in early identification of risks, preventive intervention through establishing regular lifestyle habits, learning stress management skills, and maintaining a stable social support system, without the need for special medication treatment.
II. Early traumatic experiences
Childhood traumatic experiences such as emotional neglect, physical or emotional abuse are important psychological factors that lead to depression in adulthood. These experiences may affect brain development, particularly in areas related to emotion regulation, and form insecure attachment patterns. In terms of treatment, psychotherapy is the core, such as cognitive-behavioral therapy or eye movement desensitization and reprocessing therapy, to help individuals deal with traumatic memories. Under the guidance of a doctor, antidepressants such as sertraline hydrochloride tablets and paroxetine hydrochloride tablets may also be used in combination to alleviate severe depressive symptoms.
III. Negative Cognitive Patterns
Persistent negative thinking patterns, such as pessimistic views of oneself, the world, and the future, are key psychological mechanisms for the occurrence and maintenance of depression. This pattern may manifest as excessive self blame, catastrophizing thinking, or absolute demands. Correcting this cognitive bias is the focus of treatment, usually using cognitive-behavioral therapy to help patients identify and challenge unreasonable beliefs, and establish more positive and realistic ways of thinking. At the same time, following medical advice to use medications such as escitalopram oxalate tablets and fluoxetine hydrochloride capsules can help improve mood and create conditions for psychological therapy.

4. Poor coping with long-term stress
When faced with long-term work, academic, interpersonal, or economic pressure, if an individual lacks effective coping strategies and resources and continues to consume psychological energy, it can easily lead to emotional exhaustion and depression. This may be related to long-term abnormal levels of hormones such as cortisol under chronic stress. Intervention measures include learning problem-solving skills, conducting mindfulness based stress reduction training, and adjusting unreasonable goals to alleviate stressors. When symptoms of depression are obvious, professional help should be sought. Combining psychological therapy with medication, such as using mirtazapine tablets and sustained-release capsules of venlafaxine hydrochloride, can effectively improve mood and sleep.
V. Personality traits
Certain personality traits, such as high levels of neuroticism, perfectionism tendencies, excessive dependence, or avoidant personality, may make individuals more prone to depression. These traits can affect an individual's perception and response to life events, for example, perfectionists may continue to feel frustrated due to their inability to meet high standards. In terms of treatment, long-term psychological therapy targeting personality traits, such as dialectical behavior therapy or schema therapy, has shown better results. In terms of medication treatment, doctors may choose appropriate drugs based on accompanying anxiety or emotional instability symptoms, such as agomelatine tablets, duloxetine hydrochloride enteric coated capsules, etc. for comprehensive treatment. After understanding the impact of psychological factors on depression, self-care in daily life is crucial. Maintaining a regular schedule and balanced diet, ensuring adequate sleep, can help stabilize emotions. Developing at least one hobby that can bring a sense of achievement, and consistently engaging in moderate physical exercise such as brisk walking, yoga, or swimming, can promote the secretion of endorphins and improve mood. Actively building and maintaining one's own social support network, regularly communicating feelings with trusted family and friends, and avoiding isolation. At the same time, consciously practice mindfulness meditation, learn to recognize and accept one's own emotional changes, rather than just criticizing. If you feel continuously depressed and have limited self-regulation effects, you should actively seek professional evaluation and assistance from a psychological counselor or psychiatrist. Combining psychological therapy with necessary lifestyle adjustments is an effective path towards recovery.

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