Can glucose injection be taken orally

Glucose injection is not recommended to be taken orally directly. Glucose injection is mainly administered intravenously, and oral administration may affect absorption efficiency and pose potential risks, mainly related to dosage form differences, absorption efficiency, mucosal irritation, dose control, sterilization standards, and other factors.

1. Formulation difference:

Glucose injection is a sterile aqueous solution designed specifically for intravenous injection. Its osmotic pressure and pH value are strictly adjusted to adapt to the vascular environment. Oral dosage forms usually add flavoring agents or sustained-release ingredients, while direct oral administration of injections may stimulate the gastrointestinal mucosa due to high osmotic pressure.

2. Absorption efficiency:

Intravenous injection can ensure 100% bioavailability, while oral administration requires absorption through the gastrointestinal tract, which may be affected by factors such as gastric emptying rate and intestinal microbiota interference. Emergency glucose supplementation may delay the timing of treatment. The effect is worse in some patients with absorption disorders.

3. Mucosal irritation:

High concentration glucose solution in direct contact with oral and esophageal mucosa may cause a burning sensation, and long-term oral administration may damage the mucosal barrier of the digestive tract. Patients with diabetes should be especially alert to the risk of reflux esophagitis induced by hypertonic solution.

4. Dose control: The single dose content of

injection is usually 5-50 grams, far exceeding daily oral needs. Blind oral administration may lead to sudden rise of blood sugar, reactive hypoglycemia in healthy people, and ketoacidosis in patients with diabetes.

5. Sterilization standard: Although

injection meets the sterile requirements, oral administration after opening may introduce microbial contamination. Unlike the anti-corrosion system of oral solutions, there is also a risk of accidental ingestion of glass fragments at the edge of damaged ampoules.

In special circumstances where oral glucose supplementation is required, it is recommended to use specialized oral glucose powder and rinse with warm water according to the instructions. The general population prioritizes natural foods such as bananas, honey, and other low glycemic index foods for daily energy supplementation, and timely supplements electrolyte drinks after exercise. Patients with diabetes should take sugar or glucose tablets with them to deal with hypoglycemia. Fingertip blood glucose should be monitored before use. All sugar supplementation behaviors must control the total amount, with a single intake of no more than 15 grams of carbohydrates, and retesting of blood glucose adjustment dosage every 15 minutes. When experiencing persistent symptoms of low blood sugar such as dizziness and cold sweat, immediate medical attention should be sought instead of self treatment.