Earthworm extract has five major effects on human blood vessels, including improving microcirculation, preventing thrombosis, regulating blood pressure, protecting vascular endothelium, and promoting vascular regeneration.
1. Improve microcirculation:

The fibrinolytic enzyme and earthworm kinase contained in the earthworm can decompose fibrin and reduce blood viscosity. Clinical studies have shown that these ingredients can increase the number of capillary openings, improve blood flow speed, and especially improve the retinal microcirculation in diabetes patients. Its mechanism of action is related to the activation of tissue type plasminogen.
2. Antithrombotic effect:
Earthworm extract inhibits thrombosis through a triple mechanism: directly dissolving fibrin, inhibiting platelet aggregation, and regulating coagulation factor activity. Among them, earthworm kinase can specifically degrade cross-linked fibrin, which is also effective for old thrombosis, and does not cause abnormal coagulation function, with high safety.
3. Regulating blood pressure:

The antihypertensive peptides contained in earthworm protein can inhibit the activity of angiotensin-converting enzyme and reduce the production of vasoconstrictors. Animal experiments have shown that its antihypertensive effect is stable and long-lasting, regulating both systolic and diastolic blood pressure in primary hypertension, and reducing vascular remodeling caused by hypertension.
4. Protecting vascular endothelium:
Earthworm polysaccharides can scavenge oxygen free radicals and reduce oxidative damage to vascular endothelium. Its anti-inflammatory effect can reduce the attack of inflammatory factors such as tumor necrosis factor on vascular endothelium and maintain the activity of nitric oxide synthase, which has special value for the early prevention of atherosclerosis.
5. Promote vascular regeneration:
Various growth factors in the body of Lumbricus can stimulate the migration and proliferation of endothelial cells, accelerating the establishment of collateral circulation. In the myocardial ischemia model, it was observed that the extract of Lumbricus can increase the capillary density in the infarcted area by 40%. This pro angiogenic effect is of great significance for the treatment of ischemic diseases.

Relevant active ingredients can be supplemented in daily life through methods such as earthworm protein powder and traditional Chinese medicine compound preparations. It is recommended to use them under the guidance of a doctor. Adjusting lifestyle habits such as low salt diet and aerobic exercise can better enhance its vascular protective effect. Attention should be paid to caution for individuals with allergies. The medication should be discontinued two weeks before and after surgery to avoid combination with anticoagulant drugs. Regularly monitor coagulation function and blood pressure changes, and seek medical attention promptly if there is a tendency for bleeding such as subcutaneous bruising.
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