What is the difference between 0.3 and 0.1 sodium hyaluronate

The main difference between 0.3 and 0.1 sodium hyaluronate is the concentration, with 0.3 being higher than 0.1 and suitable for more severe joint lubrication deficiencies or dry eye conditions. Sodium hyaluronate is a viscoelastic substance commonly used for intra-articular injection or eye drops, and concentration differences can affect its viscosity, retention time, and therapeutic effect. A 0.3 concentration sodium hyaluronate solution has higher viscosity, longer residence time in the joint cavity, and can provide more lasting lubrication and buffering effects, making it suitable for patients with moderate to severe osteoarthritis. Its molecular chain is longer, which has a more significant protective effect on cartilage and can reduce joint friction pain. When applied in ophthalmology, high concentration formulations can more effectively alleviate corneal dryness damage in patients with severe dry eye syndrome, but may result in temporary blurred vision. A 0.1 concentration sodium hyaluronate solution has better fluidity and is suitable for early joint lesions or mild dry eye symptoms. Its osmotic pressure is low, and the pain during injection is mild, making it suitable for patients who are sensitive to pain. When used in ophthalmology, there is less foreign body sensation, which is suitable for preventive care of mild eye dryness in daily life, but more frequent infusion is needed to maintain the effect. The specific concentration of SEP should be determined based on the severity of the condition, tolerance, and physician evaluation. Before use, contraindications such as active infection and bleeding tendency should be ruled out. After joint injection, vigorous exercise should be avoided. If there is persistent discomfort after using eye drops, they should be discontinued. Different brands may have differences in purity and additives, so there is no need to adjust the concentration by oneself.