What does a low absolute value of lymphocytes indicate

A low absolute value of lymphocytes may indicate abnormal immune function, commonly seen in the recovery period of viral infection, long-term use of immunosuppressants, radiation exposure, and a few may be related to hematological diseases. Lymphocytes are important immune cells in the human body, and their numerical abnormalities need to be comprehensively judged in conjunction with other indicators.

During the recovery period of viral infection, there may be a temporary decrease in lymphocytes, which is related to the virus inhibiting bone marrow hematopoietic function. At this time, it is usually accompanied by an increase in the proportion of neutrophils, which belongs to the body's stress response. Long term use of immunosuppressants such as glucocorticoids and anti-tumor drugs can directly inhibit lymphocyte production, and such situations require regular monitoring of blood routine. The bone marrow suppression period after radiation examination or treatment can also lead to a decrease in lymphocytes, which can gradually recover within 1-2 months. Persistent lymphocyte depletion requires vigilance against hematological diseases. Patients with aplastic anemia often have a decrease in whole blood cells and a significant decrease in the absolute value of lymphocytes. Some lymphomas may experience treatment-related lymphocyte depletion after chemotherapy. The specific attack of AIDS virus on CD4+T lymphocytes will cause a continuous decline in this subset of cells. Diseases such as myelodysplastic syndrome may also affect lymphocyte differentiation and maturation. When the absolute value of lymphocytes is found to be low, it is recommended to recheck the blood routine and improve the analysis of lymphocyte subsets. Daily attention should be paid to preventing infections, avoiding crowded places, and ensuring sufficient nutrient intake. If there are symptoms such as persistent fatigue and recurrent fever, medical attention should be sought in a timely manner, and further examinations such as bone marrow puncture should be performed if necessary. People with weakened immune function can receive preventive vaccines such as pneumonia vaccine and influenza vaccine according to medical advice.