At present, there is no single most effective weight loss medication, and the selection of weight loss medication needs to be guided by a doctor based on individual circumstances. Common prescription weight loss medications include Orlistat capsules, Liraglutide injection, Fentrametine hydrochloride sustained-release tablets, naltrexone sustained-release tablets, and Chlorhexidine tablets.

1. Orlistat Capsules
Orlistat capsules are a gastrointestinal lipase inhibitor that achieves weight loss by reducing the absorption of dietary fat. They are suitable for obese patients with a body mass index exceeding 28. This medicine may cause adverse reactions such as fat diarrhea and gastrointestinal bloating, and long-term use requires monitoring of fat soluble vitamin levels. During use, it is necessary to follow a low-fat diet and should not be used for patients with chronic malabsorption syndrome or cholestasis.
2. Lilalutide injection
Lilalutide injection is a GLP-1 receptor agonist, which helps to reduce weight by delaying gastric emptying and increasing satiety, and is suitable for type 2 diabetes patients with obesity. Common side effects include gastrointestinal reactions such as nausea and vomiting, which may increase the risk of pancreatitis. Please note that this medication should be administered subcutaneously and is not recommended for patients with a history of medullary thyroid cancer or multiple endocrine neoplasia.
3. Fentrametin Hydrochloride Extended Release Tablets
Fentrametin Hydrochloride Extended Release Tablets are a combination of appetite suppressants and antiepileptic drugs, which exert their effects through central appetite suppression and are suitable for simple obesity with a body mass index exceeding 30. May cause adverse reactions such as dry mouth, constipation, and sensory abnormalities, and is contraindicated for patients with glaucoma, hyperthyroidism, and cardiovascular disease. Regular monitoring of blood pressure and heart rate is required during medication.

4. Naltrexone Extended Release Tablets
Naltrexone Extended Release Tablets are opioid receptor antagonists that reduce weight by regulating the central appetite control system. They are suitable for obese patients with ineffective dietary control. Common adverse reactions include nausea, headache, insomnia, etc. It is contraindicated for those with severe liver and kidney dysfunction. This medication may increase the risk of suicidal thoughts, and patients with depression should use it with caution.
5. Chlorhexidine Tablets
Chlorhexidine tablets are 5-HT2C receptor agonists that reduce food intake by enhancing satiety. They are suitable for patients with a body mass index greater than 27 and obesity related complications. May cause side effects such as headache, dizziness, fatigue, etc., and should not be used in combination with monoamine oxidase inhibitors. During use, the risk of heart valve disease should be monitored, and it is contraindicated for patients with pulmonary hypertension.

Weight loss drugs need to be used under the supervision of a doctor, combined with dietary control and exercise to achieve optimal results. It is recommended to engage in 150 minutes of moderate intensity aerobic exercise per week, such as brisk walking, swimming, etc., while adopting a low calorie balanced diet and reducing daily calorie intake by 500-750 calories. Establish regular sleep habits, ensure 7-8 hours of sleep, avoid staying up late and emotional eating. Regularly monitor changes in weight, waist circumference, and body fat percentage, and immediately discontinue medication and seek medical attention in case of serious adverse reactions. During the weight loss process, seek guidance from a nutritionist to develop personalized plans and avoid blindly using weight loss pills or extreme dieting methods.
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