Ketogenic weight loss may lead to hazards such as hypoglycemia, electrolyte imbalance, increased burden on liver and kidney function, increased cardiovascular risk, and nutritional imbalance. The ketogenic diet forces the body to burn fat for energy through extremely low carbohydrate intake, but long-term implementation may lead to various health problems.

1. Hypoglycemia
A ketogenic diet with strict control of carbohydrate intake may lead to a sudden drop in blood sugar levels. Early symptoms include dizziness, fatigue, hand tremors, and other hypoglycemic symptoms. In severe cases, confusion or even coma may occur. Patients with diabetes or insulin resistance are at higher risk, and blood glucose changes need to be closely monitored.
2. Electrolyte disorders
During the initial stage of ketogenesis, a large amount of water loss can take away electrolytes such as sodium, potassium, and magnesium, causing muscle spasms, palpitations, or arrhythmia. Some people may experience "ketogenic influenza", manifested as headaches, nausea, and fatigue, which is closely related to electrolyte imbalance.
3. Liver and kidney burden
Metabolism of ketone bodies can increase liver workload, which may lead to fatty liver or liver dysfunction in the long term. High protein intake can increase renal filtration pressure, and patients with chronic kidney disease may accelerate renal function deterioration. Elevated uric acid may also trigger gout attacks.

4. Cardiovascular risk
High fat diet may increase low-density lipoprotein cholesterol and increase the probability of atherosclerosis. Excessive intake of saturated fatty acids is associated with cardiovascular and cerebrovascular diseases, especially for those with a history of dyslipidemia or hypertension.
5. Nutritional deficiency
Restricting foods such as grains and fruits can lead to insufficient intake of B vitamins, vitamin C, and dietary fiber. Lack of minerals such as calcium and magnesium may affect bone health and may lead to long-term problems such as constipation and weakened immunity. Before implementing a ketogenic diet, a comprehensive health assessment should be conducted to avoid blind experimentation. It is recommended to develop personalized plans under the guidance of nutritionists and regularly monitor indicators such as blood ketones and liver and kidney function. During the transition period, it is recommended to supplement electrolyte drinks and choose healthy fat sources such as olive oil and avocado. If there is persistent fatigue, palpitations, or discomfort in the digestive system, timely medical attention should be sought to adjust the diet structure. It is necessary to ensure sufficient water intake in daily life and maintain muscle mass through moderate resistance exercise.

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