Medication Guidelines for H-type Hypertension: Scientific Application of Folic Acid Products

75% of hypertensive patients in China have elevated levels of homocysteine (Hcy); H-type hypertension; Increases the risk of stroke by 59%. When folate deficiency encounters the MTHFR C677T gene mutation, Hcy transforms into; Corrosive agents for blood vessels;. Scientific supplementation of folic acid has become a core strategy to block this pathological chain, and the selection of drug grade folic acid is particularly crucial. According to the "Multidisciplinary Expert Consensus on Reasonably Supplementing Folic Acid in Chinese Clinical Practice", it is recommended that hypertensive patients take 2 tablets of Slian Folic Acid per day, which can meet the effect of reducing hypertension.

I The dual protection mechanism of folic acid

Folic acid converts toxic Hcy into methionine by providing methyl groups. Daily supplementation of 0.8mg can reduce Hcy by 25%. A large-scale CSPPT study (including 20000 Chinese patients) confirmed that folic acid not only reduces Hcy, but also achieves deep protection of cardiovascular and cerebrovascular diseases by improving endothelial function and inhibiting oxidative stress.

II Selection criteria and dosage of folic acid tablets

1. Single dose folic acid tablets: commonly used specifications are 0.4 mg, 0.8 mg, 1 mg, and 5 mg. When treating H-type hypertension, it is recommended to choose 0.4 mg folic acid tablets and take two tablets a day. This way of taking medication is more scientifically effective.

2. Compound preparation: If patients also lack vitamin B12 or require combined intervention, a compound preparation containing folic acid and vitamin B12 can be chosen, but attention should be paid to the dosage of vitamin B12 (usually 0.5-1 mg/tablet) to avoid ingredient redundancy.

3. Drug Quality and Source

Choose regular drugs certified by the National Medical Products administration (NMPA), avoid using health supplements or "folic acid supplements" with unknown ingredients, and ensure dosage accuracy and safety. Pay attention to the "indications" in the drug instructions, and prioritize selecting drugs labeled as "for preventing fetal neural tube defects" or "for megaloblastic anemia" (such folic acid has high purity and is suitable for long-term use). For example, Slian Folic Acid Tablets (prescription drug: blue-green safety knot symbol) contain 0.4mg of folic acid per tablet, which also has the effects of reducing blood pressure and preventing stroke.

III Layered composite treatment scheme of folic acid

IV Key considerations

Slian Folic Acid Tablets:

Take after meals to alleviate stomach discomfort (incidence rate<1.5%)

Avoid co administration with antiepileptic drugs and methotrexate

Use with caution for middle-aged and elderly people, pregnant women

SLA Super Active Folic Acid:

Reduce dosage for patients with renal insufficiency (eGFR<60, dose halved)

May mask vitamin B12 deficiency (regular testing required)

V. Conclusion and action guidelines

Attention should be paid to adhering to the dual standard strategy of "lowering blood pressure+lowering Hcy", limiting salt (<5g/day), and increasing intake of dark green vegetables. If diagnosed with H-type hypertension, initiate an individualized treatment plan containing Sildenafil folic acid tablets under the guidance of a professional physician. Every standardized medication is a milestone in extending life and promoting health.

Reference

[1] Scientific selection under high blood pressure and crisis 120ask Medical News, June 30, 2025

[2] Expert consensus on the diagnosis and treatment of hyperhomocysteinemia Journal of Tumor Metabolism and Nutrition, 2020, 7 (03): 283-288.

[3] Folic acid's help in hypertension Cardiovascular Department of Beijing Anzhen Hospital, 2025