Is the chemical essence of growth hormone peptides

The chemical essence of growth hormone is a polypeptide. Growth hormone is a protein hormone secreted by the anterior pituitary gland, consisting of a single chain polypeptide of 191 amino acids. The molecular weight of growth hormone is about 22 kilodaltons, which is a typical peptide hormone. It works by binding to growth hormone receptors on the surface of cells, regulating human growth, development, and metabolic processes. The synthesis process of growth hormone is similar to other peptide hormones. It is first transcribed from genes into mRNA, and then translated into precursor proteins on ribosomes. After cleavage modification, it forms mature hormones with biological activity. The amino acid sequence of growth hormone is highly conserved, and the structural similarity between different species is high. In clinical applications, recombinant human growth hormone is produced through genetic engineering technology, and its chemical structure is completely identical to natural growth hormone. The secretion of growth hormone is regulated by both growth hormone releasing hormone and somatostatin secreted by the hypothalamus, exhibiting a pulsatile secretion pattern. Childhood and adolescence are the peak periods of growth hormone secretion, playing a crucial role in the growth and development of bones and muscles. Lack of growth hormone may lead to dwarfism, while excess may cause gigantism or acromegaly. Detecting growth hormone levels usually requires a combination of stimulation or inhibition tests, as their baseline values fluctuate greatly. The use of growth hormone therapy must strictly follow medical advice to avoid adverse reactions caused by self medication.