Is the average red blood cell volume 121 severe

The average red blood cell volume of 121 belongs to the high range, which may indicate the presence of problems such as large cell anemia, but it needs to be comprehensively judged in combination with other indicators. The average red blood cell volume is an important indicator in blood routine examination, and the normal reference range is usually between 80-100 liters. When the value reaches 121, it significantly exceeds the upper limit of normal, which is common in large cell anemia caused by vitamin B12 or folate deficiency. Patients may experience symptoms such as fatigue, decreased appetite, and pale skin, which may affect neurological function if left uncorrected for a long time. Laboratory error factors should be excluded during testing. It is recommended to take blood on an empty stomach and avoid testing immediately after intense exercise. In rare cases, an increase in average red blood cell volume may be associated with conditions such as myelodysplastic syndrome, liver disease, or hypothyroidism. These diseases are often accompanied by abnormalities in other blood routine indicators, such as changes in white blood cell or platelet count. Long term use of certain drugs such as antiepileptic drugs may also lead to an increase in this indicator, which needs to be analyzed in conjunction with medication history. Alcohol abusers often experience an increase in red blood cell volume due to nutritional absorption disorders. When the average red blood cell volume is consistently high, it is recommended to improve serum vitamin B12 and folate concentration testing, and if necessary, perform bone marrow puncture examination. Daily attention should be paid to a balanced diet, with an appropriate increase in foods rich in vitamin B12 and folate, such as animal liver and dark green vegetables. Avoid excessive alcohol consumption, regularly check changes in blood routine indicators, and have a doctor evaluate whether medication intervention is needed.