The accuracy of NT anomaly detection is relatively high, but not absolutely accurate. NT examination mainly evaluates the risk of chromosomal abnormalities by measuring the thickness of the fetal nuchal translucency, which has certain reference value for screening chromosomal diseases such as Down syndrome. The factors that affect accuracy include the precision of ultrasound equipment, operator experience, fetal position, and calculation errors of gestational age. The NT test is most reliable when performed between 11-13 weeks and 6 days of pregnancy, and when combined with serological screening, it can improve the detection rate. Normal NT values are usually less than 2.5 millimeters, and numerical thickening may be associated with chromosomal abnormalities, congenital heart disease, or fetal edema. However, it should be noted that about 5% of normal fetuses may also experience temporary thickening of the NT, which needs to be confirmed by subsequent non-invasive DNA or amniocentesis. In some special cases, false negative or false positive results may occur. If poor fetal position leads to measurement deviation, or incorrect calculation of gestational age affects judgment. Some structural abnormalities that are not yet apparent in early pregnancy may also lead to missed diagnosis. For high-risk pregnant women, it is recommended to further confirm through diagnostic tests such as chorionic villus sampling and amniocentesis.
During pregnancy, systematic prenatal screening including NT examination should be completed on time, and a reasonable diet and sufficient rest should be maintained. Avoid excessive anxiety when discovering abnormal indicators and consult professional doctors for personalized evaluation in a timely manner. Subsequently, multidimensional evaluations of fetal development can be conducted in conjunction with prenatal ultrasound, fetal cardiac ultrasound, and other examinations. Genetic counseling may be necessary if necessary.
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