Is prothrombin time 10.6 normal

Prothrombin time of 10.6 seconds is generally within the normal range. Prothrombin time is mainly used to evaluate the function of exogenous coagulation pathways. The reference value for adults is usually 11-14 seconds, but the testing equipment and reagents in different laboratories may result in slight differences in the results. The prothrombin time of 10.6 seconds is slightly lower than the lower limit of the conventional reference value, which may indicate mild hyperfunction of coagulation function. This situation is common when there is sufficient intake of vitamin K in the diet, recent intake of vitamin K supplements, or foods rich in vitamin K such as spinach and broccoli. Some populations may have higher natural coagulation factor activity due to genetic factors, and may also have lower test values. If there was a large amount of drinking water or slight hemolysis in the blood sample before the test, it may also affect the accuracy of the results. In rare cases, low prothrombin time may be associated with pathological conditions. Patients with early-stage disseminated intravascular coagulation hypercoagulability, early thrombotic disease, or certain tumors may have elevated levels of fibrinogen. Long term use of glucocorticoids or oral contraceptives may also lead to an increase in coagulation function. If there are other coagulation indicators such as abnormal platelet count and elevated D-dimer, further investigation of potential causes is needed.

It is recommended to comprehensively evaluate indicators such as activated partial thromboplastin time and fibrinogen. If there is no history of bleeding or thrombosis and other coagulation indicators are normal, regular follow-up monitoring can be conducted. Avoid excessive supplementation of vitamin K in daily life and maintain a balanced diet. If surgery is required or there is a long-term need for medication, the doctor should be informed in advance of the coagulation function test results.