Is Orlistat for weight loss or weight control

Orlistat is mainly used for weight control rather than direct weight loss, and is suitable for weight management in overweight or obese populations. Orlistat is a gastrointestinal lipase inhibitor that works by reducing dietary fat absorption and should be used in conjunction with a low calorie diet. Orlistat inhibits lipase activity in the gastrointestinal tract, preventing about one-third of dietary fat from being broken down and absorbed. Unabsorbed fat is excreted with feces. This mechanism makes it more suitable for long-term weight control rather than rapid weight loss. Clinical data shows that regular medication combined with dietary adjustments can lead to an average weight loss of 5% -10% for overweight individuals, but individual differences are significant. During use, adverse reactions such as oily spots and increased gastrointestinal exhaust may occur. It is recommended to start adapting from low doses.

It should be noted that orlistat is not effective for all types of obesity and has a better effect on simple obesity, but its effect is limited in populations with endocrine disorders or genetic obesity. Patients with severe liver and kidney dysfunction and chronic malabsorption syndrome are contraindicated. During medication, additional fat soluble vitamins should be supplemented to avoid malnutrition caused by impaired fat absorption.

It is recommended to include orlistat as part of a comprehensive weight management plan, along with aerobic exercise for at least 30 minutes per day and a balanced diet. Long term use should be evaluated for effectiveness every 3 months, and if weight loss is not significant, the plan should be adjusted. After the weight stabilizes, medication should be gradually stopped and a lifestyle maintained to avoid rebound. It is recommended to consult before medication to develop a personalized plan based on body mass index and health status.