Is long-term consumption of sildenafil harmful

Long term use of sildenafil may have certain effects on the body, but the specific harm varies from person to person. Sildenafil is mainly used to treat male erectile dysfunction, and its safety has been verified in short-term use, but long-term continuous use requires caution. Special populations such as cardiovascular disease patients, those taking nitrate drugs, and those with abnormal liver function are at higher risk. Before use, the individual's health condition should be fully evaluated and medical advice should be strictly followed. Sildenafil improves penile blood flow by inhibiting phosphodiesterase 5, and short-term use is relatively safe for most people. Common adverse reactions include headaches, facial flushing, indigestion, etc., which are usually mild and reversible. Regular sleep, moderate exercise, balanced diet and other lifestyle adjustments may reduce drug dependence. Regular monitoring of blood pressure and heart function can help detect potential problems early. Long term overuse of SEP may lead to increased drug tolerance, forcing an increase in dosage to achieve the same effect. Some users may experience rare but serious side effects such as visual abnormalities or hearing loss. When using antihypertensive or antidepressant drugs in combination, the risk is superimposed, which may lead to hypotension or serotonin syndrome. Although there are few cases of sudden cardiac death in patients with hidden cardiovascular disease after medication, caution should be taken.

It is recommended that individuals with long-term medication needs undergo cardiovascular system assessments every 3-6 months, including electrocardiograms and exercise stress tests. Daily attention should be paid to observing whether there are danger signals such as chest pain and continuous erection for more than 4 hours. Foods rich in antioxidants such as broccoli and deep-sea fish may assist in reducing vascular endothelial damage. During medication, alcohol and high-fat diet should be strictly avoided, as these factors may affect drug metabolism and increase the risk of side effects.