How to treat excessive obesity caused by adrenal glands

Excessive obesity caused by adrenal glands usually requires comprehensive treatment based on the causes, mainly including drug therapy, surgical treatment, lifestyle adjustments, hormone replacement therapy, and regular monitoring. Diseases such as adrenal cortex hyperfunction, Cushing's syndrome, and adrenal adenoma may lead to such obesity, and personalized plans need to be developed by endocrinologists.

1. Drug therapy

is used to treat abnormal secretion of adrenal hormones. Commonly used drugs include ketoconazole, mitoxan, and metoprolol, which can inhibit cortisol synthesis. For secondary hypertension or abnormal blood sugar, it may be necessary to use antihypertensive or hypoglycemic drugs in combination. During medication, strict monitoring of liver and kidney function and hormone levels is necessary to avoid self adjustment of dosage.

2. Surgical treatment

For obesity caused by adrenal tumors, laparoscopic adrenalectomy or open surgery can be selected after evaluation. postoperative obesity in patients with unilateral benign adenomas can often be relieved, but for malignant tumors, the resection range needs to be expanded. Long term follow-up of hormone levels is required after surgery, and some patients may experience adrenal insufficiency.

3. Lifestyle Adjustment

A low salt, low sugar, high protein diet can help control weight and blood pressure, and daily sodium intake should be less than 3 grams. It is recommended to engage in low impact exercises such as swimming and brisk walking, accumulating at least 150 minutes per week. Sleep management is crucial for regulating cortisol rhythms, and it is necessary to ensure 7-8 hours of regular sleep per day.

4. Hormone replacement therapy [SEP]: When postoperative or drug-induced adrenal dysfunction occurs, hydrocortisone or fluorohydrocortisone should be supplemented. The replacement dose needs to be dynamically adjusted according to the stress state, and temporary increments are required in cases of infection, surgery, etc. During the treatment period, it is necessary to be alert to complications such as osteoporosis and electrolyte imbalance.

5. Regular monitoring

Recheck cortisol rhythm every 3-6 months ACTH、 Abdominal CT and other indicators. Child patients need to be monitored for growth and development curves, and women of childbearing age should pay attention to changes in their menstrual cycle. When there are signs of weight rebound, increased purple lines, etc., it is necessary to promptly follow up and adjust the plan. The treatment cycle for adrenal derived obesity is relatively long, and patients should establish standardized follow-up records, including daily blood pressure, blood glucose, and weight data. In terms of diet, foods rich in vitamin D and calcium such as dairy products and deep-sea fish can be added, while avoiding ingredients such as licorice that affect hormone metabolism. The exercise plan should be gradual and incremental, starting from 15 minutes per day. For those with osteoporosis, they should avoid vigorous running and jumping. psychological support is equally important, and joining patient support groups can help alleviate anxiety. If there is obvious fatigue, dizziness, or edema during the treatment period, immediate medical attention should be sought to assess hormone levels.