Does obesity affect the causes of infertility in girls

Obesity may affect female infertility, mainly related to endocrine disorders, ovulation disorders, polycystic ovary syndrome, endometrial abnormalities, metabolic syndrome, and other factors.

1. Endocrine disorders

Obesity can lead to excessive secretion of estrogen from adipose tissue, disrupting the function of the hypothalamic pituitary ovarian axis. Abnormal elevation of estrogen levels in the body may inhibit follicular development and affect normal menstrual cycles. Long term endocrine disorders may further lead to luteal insufficiency and reduce the probability of conception.

2. Ovulation disorders

Overweight women often experience anovulatory menstruation, and leptin resistance produced by adipocytes may affect the release of gonadotropins. Obesity induced insulin resistance can stimulate the ovaries to secrete excessive androgens, inhibiting the formation of dominant follicles. Clinical manifestations include infrequent or absent menstruation, which directly affects fertility.

3. Polycystic ovary syndrome

Obesity is an important cause of polycystic ovary syndrome, where multiple small follicles in the ovaries stagnate in development. Kaohsiung hormone status leads to symptoms such as acne and hirsutism, accompanied by abnormal glucose and lipid metabolism. This pathological change makes natural conception difficult and requires medical intervention.

4. Endometrial abnormalities

inflammatory factors produced by adipose tissue may impair endometrial receptivity and affect embryo implantation. Obese women often have proliferative changes in the endometrium, and progesterone resistance is more common. Even if successful conception occurs, it may increase the risk of early miscarriage.

5. Metabolic syndrome

Obesity related insulin resistance can lead to compensatory hyperinsulinemia, a metabolic disorder that may impair egg quality. The accompanying complications such as hypertension and dyslipidemia will also increase obstetric risks such as diabetes in pregnancy and pre eclampsia, and indirectly affect the reproductive outcome.

For obese women, it is recommended to improve fertility through scientific weight loss. Adopting a low glycemic index diet combined with aerobic exercise, the weekly weight loss is controlled within a reasonable range. If necessary, medication that improves insulin sensitivity, such as metformin, can be used under the guidance of a doctor. Before preparing for pregnancy, it is necessary to comprehensively evaluate metabolic indicators and adjust lifestyle accordingly. The weight loss process should be gradual and avoid extreme dieting that can lead to nutritional imbalance. Regularly monitor ovulation and seek assistance from reproductive medicine specialists if necessary.