Do normal people lose weight by taking metformin

Normal individuals do not need to lose weight by taking metformin. Metformin is a prescription drug for the treatment of type 2 diabetes. Its weight reduction effect is mainly aimed at obese diabetes patients with insulin resistance. The use of metformin in healthy people may cause gastrointestinal discomfort, vitamin B12 deficiency and other adverse reactions.

Metformin plays a role by inhibiting hepatic glucose output and improving insulin sensitivity, and has an auxiliary effect on weight control of diabetes patients. But the metabolic mechanism of healthy individuals is normal, and drug intervention may interfere with physiological balance. Common adverse reactions include gastrointestinal reactions such as diarrhea and nausea, and long-term use may also affect the absorption of vitamin B12. Some people may be at risk of lactic acidosis, especially those with liver and kidney dysfunction who need to be contraindicated. Weight loss should be achieved through a reasonable diet and exercise, and medication intervention should strictly follow medical advice.

It is recommended to achieve healthy weight loss by adjusting dietary structure, controlling total calorie intake, and combining aerobic exercise and strength training. Avoid high sugar and high-fat diets, increase intake of whole grains, vegetables, and high-quality protein. If there are metabolic abnormalities or difficulties in weight management, individualized plans should be developed after medical evaluation, and hypoglycemic drugs should not be used on one's own.