Constipation caused by taking weight loss pills but losing weight

Constipation but weight loss after taking weight loss pills may be related to the drug ingredients inhibiting gastrointestinal motility or reducing water absorption. Constipation caused by weight loss drugs is mainly due to the stimulation of drug ingredients, insufficient intake of dietary fiber, imbalance of gut microbiota, insufficient water intake, metabolic disorders, and other reasons. Corresponding measures need to be adjusted according to specific drug types.

1. Drug composition stimulation

Some weight loss drugs contain diuretics or appetite suppressants such as sibutramine, which may reduce hunger by inhibiting the central nervous system and slow down intestinal peristalsis, leading to constipation. Accompanying symptoms include dry mouth and palpitations. Follow the doctor's advice to use osmotic laxatives such as lactulose oral solution and polyethylene glycol 4000 powder to relieve symptoms, and avoid long-term use of irritating laxatives such as senna granules.

2. Insufficient dietary fiber intake

During weight loss, excessive control of diet can lead to insufficient intake of vegetables and fruits, and a lack of dietary fiber can cause a decrease in stool volume and an increase in hardness. It is recommended to supplement 20-30 grams of dietary fiber daily, choose soluble fibers such as oat bran and chia seeds, and use flaxseed oil to regulate intestinal lubrication, while avoiding sudden increases in fiber content that can cause bloating.

3. Imbalance of gut microbiota

Some weight loss drugs may alter the pH value of the intestine or directly inhibit the growth of probiotics, resulting in alternating constipation and diarrhea. After detecting the gut microbiota, probiotics such as Bifidobacterium triple active capsules and Bacillus subtilis double active granules can be supplemented, combined with prebiotics such as oligofructose to promote colonization and avoid co administration with antibiotics.

4. Insufficient water intake

Body fluid loss caused by weight loss pills or deliberate reduction of water intake can lead to increased colonic water reabsorption and dry stool. It is recommended to drink 1.5-2 liters of warm water daily, divided into small amounts. A small amount of lemon juice can be added to stimulate intestinal peristalsis, but it should be taken at least 2 hours apart from diuretic weight-loss drugs.

5. Metabolic disorders

Thyroid dysfunction or electrolyte imbalance may be induced by weight loss drugs, manifested as refractory constipation with sudden weight loss. Thyroid hormone and blood potassium levels need to be tested to rule out hyperthyroidism or hypokalemia. If necessary, levothyroxine sodium tablets should be used to regulate metabolism. Stimulating laxatives should be avoided to avoid exacerbating electrolyte loss. When constipation occurs accompanied by obvious abdominal pain, rectal bleeding, or continuous weight loss, immediately stop taking weight loss pills and seek medical attention. Daily recommendations include moderate exercise such as jogging and yoga to promote intestinal peristalsis, drinking 300ml of warm water before breakfast, consuming natural laxatives such as dragon fruit and sugar free yogurt, and establishing a regular bowel habit. Long term use of weight loss pills may cause intestinal nerve damage, and should be gradually reduced under the guidance of a doctor.