Can normal people lose weight by taking metformin

It is not recommended for normal people to lose weight by taking metformin. Metformin is a prescription drug for the treatment of type 2 diabetes. Its weight loss effect is limited and there are potential risks.

The weight loss mechanism of metformin is mainly achieved by inhibiting liver glycogen output and improving insulin sensitivity. For non diabetes patients, it may only cause slight weight loss. Common adverse reactions of this drug include gastrointestinal discomfort, diarrhea, nausea, etc. Long term use may lead to vitamin B12 deficiency. The use of it by healthy individuals may disrupt normal metabolic balance, and there is a lack of evidence-based medicine to support its safety and effectiveness as a weight loss medication.

For people with pre diabetes or insulin resistance, doctors may use metformin for short-term metabolic management according to specific conditions, but blood glucose and liver and kidney functions need to be strictly monitored. Simple obesity may mask potential metabolic problems and delay the optimal timing for lifestyle interventions. Weight loss should be achieved through scientific dietary control and regular exercise. It is recommended to maintain aerobic exercise for at least 30 minutes daily, increase intake of vegetables, fruits, and whole grains in the diet, and limit refined sugars and saturated fats. If medication intervention is needed, nationally approved weight loss drugs should be selected under the guidance of a doctor, and self use of hypoglycemic drugs should be avoided. Regularly monitor changes in body fat percentage and waist circumference, and establish a long-term health management plan.