Can Losing Weight by 15kg diabetes Reverse

Losing 15kg may help to improve the condition of diabetes, but whether it can be completely reversed depends on individual conditions. The reversal of diabetes is related to the extent of weight loss, duration of disease, islet function and other factors.

Overweight or obese type 2 diabetes patients can significantly improve insulin sensitivity through weight loss. Clinical observations have shown that some patients can return to normal blood sugar levels after losing 10-15% weight. This is mainly due to the increased responsiveness of the liver and muscles to insulin after the reduction of adipose tissue, as well as partial recovery of pancreatic beta cell function. For patients with a shorter course of disease and better islet function retention, a weight loss of 15 kg may achieve remission of diabetes, and even some patients may temporarily stop taking hypoglycemic drugs. But sustained lifestyle interventions are needed to maintain effectiveness. Patients with a disease course of more than 5 years or severe pancreatic dysfunction have a lower probability of complete reversal after weight loss. These patients often require long-term medication treatment, and weight loss mainly serves as an auxiliary glycemic control function. Type 1 diabetes and late type 2 diabetes usually cannot reverse the disease process due to a large number of apoptotic islet cells. In addition, patients with specific genetic variations or pancreatic organic lesions have limited effects of weight loss on blood glucose improvement.

It is recommended that diabetes patients develop personalized weight loss programs under the guidance of doctors, and adopt a combination of scientific diet and regular exercise. 150 minutes of moderate intensity aerobic exercise per week, combined with resistance training, yields better results. Diet should control total calorie intake and increase the proportion of vegetables, fruits, and whole grains. During the weight loss process, it is necessary to regularly monitor changes in blood sugar levels to avoid the occurrence of hypoglycemia. Even if the blood sugar level reaches the normal range, it is still recommended to undergo glycated hemoglobin testing annually and continue to monitor metabolic status.