Weight loss pills should not be taken casually, as overuse may cause serious side effects such as palpitations and liver and kidney function damage. The use of weight loss drugs should strictly follow medical advice, mainly suitable for people with BMI ≥ 28 or comorbid obesity related diseases. Common types include appetite suppressants, lipase inhibitors, GLP-1 receptor agonists, etc.
1. cardiovascular risk:
Some weight loss drugs containing ephedrine and caffeine can stimulate the sympathetic nervous system, leading to increased heart rate and blood pressure. There have been cases of ventricular arrhythmia caused by taking illegal weight loss drugs in clinical practice, and patients with hypertension and coronary heart disease have a higher risk.
2. Metabolic system effects: Lipase inhibitors such as orlistat may cause lipid soluble vitamin deficiency, and long-term use can lead to malnutrition. Some drugs interfere with glucose metabolism, and patients with diabetes may suffer from hypoglycemia or ketoacidosis.
3. Hepatorenal toxicity:
The liver is the main organ for drug metabolism, and components such as sibutramine may cause elevated transaminase levels. The use of diuretics for weight loss in patients with renal insufficiency can exacerbate electrolyte imbalances and, in severe cases, lead to acute kidney failure.
4. Mental dependence:
Amphetamine appetite suppressants are addictive, and sudden discontinuation of medication can lead to withdrawal symptoms such as depression and anxiety. Some people develop drug dependence due to excessive pursuit of weight loss effects, which in turn leads to eating disorders such as binge eating.
5. Hidden dangers of counterfeit drugs:
Online sales of "internet famous weight loss drugs" often illegally add prohibited ingredients such as sibutramine and phenolphthalein. In a typical case reported by the National Medical Products administration in 2022, a certain WeChat business product detected a dosage of sibutramine that exceeded the standard by 600 times.
It is recommended to control daily calorie intake by adjusting the diet structure and adopting a high protein, high fiber, low GI diet pattern. Combining aerobic exercise and resistance training, maintain 150 minutes of moderate intensity exercise per week. If medication intervention is needed, one should go to the endocrinology department of a regular hospital for evaluation, choose nationally approved regular drugs under the guidance of a doctor, and regularly monitor blood pressure, blood sugar, liver and kidney function and other indicators during medication. Postpartum women, middle-aged and elderly people, and other special populations need to be cautious with medication and avoid purchasing weight loss products from unknown sources on their own.
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