Why should Anhui Zhifei take three shots of COVID-19 vaccine? How long is the interval between each shot of COVID-19 vaccine

Recently, due to the targeting of COVID-19 vaccination population, in order to meet the market supply, Anhui Zhifei COVID-19 vaccine has been approved for mass production. At present, many provinces are vaccinated with Anhui Zhifei recombinant novel coronavirus vaccine (CHO cell), which is different from the inactivated vaccine. So, how long is the interval between three shots of Anhui Zhifei COVID-19 vaccine? Why do we need to get three injections? Let me answer a few questions for you below!

I. How long is the interval between three injections of Anhui Zhifei COVID-19 vaccine?

The interval between three injections of Anhui Zhifei COVID-19 vaccine is one month. According to the vaccination procedure, three doses of recombinant COVID-19 vaccine need to be inoculated, which will be completed in 0, 1, and 2 months respectively, 60 days before and after the vaccination. The recommended interval for vaccination between adjacent doses is 4 weeks. The second dose should be completed within 8 weeks after the first dose, and the third dose should be completed within 6 months after the first dose. If you still don't understand, you can consult the nurse at the hospital where you received the vaccination, and they will usually inform you of the specific time for the next dose. Can the third dose of Anhui Zhifei vaccine be skipped?

It is not recommended not to receive the third dose. Because Anhui Zhifei COVID-19 uses the three needle method for vaccination, the interval between each needle may be different. After two injections, 76% of the antibody can be reached, and after three injections, 97% of the antibody can be reached. So it is necessary to receive three doses.

2. Is an injection of Anhui Zhifei vaccine effective? The effect of one dose of Anhui Zhifei vaccine is not very obvious. Generally, a certain amount of antibodies are produced after the second dose, and after three doses, the antibodies will reach more than 90%.

3. How often does Anhui Zhifei COVID-19 Vaccine take the second shot?

After the first injection of Anhui Zhifei COVID-19 Vaccine, it is recommended that the second injection be administered within 4 weeks or more, that is, the second injection should be administered within 8 weeks as far as possible.

4. When will the third injection of Anhui Zhifei COVID-19 vaccine be given?

The third dose of Anhui Zhifei COVID-19 vaccine is recommended to be vaccinated 4 weeks or more after the second dose, that is, after the first dose, try to complete the third dose within 6 months.

II. Why did Anhui Zhifei COVID-19 Vaccine get three shots?

1. Reason 1: Different vaccine types

Anhui Zhifei COVID-19 vaccine is a vaccine with recombinant immune protein, and different vaccine plays are different. For example, the inactivated COVID-19 vaccine needs two shots to get immunity, while the adenovirus vector vaccine needs one shot, which can produce effective protection 14 days later.

2. Reason 2: The effect is more obvious

According to the clinical trial data of Anhui Zhifei recombinant COVID-19 vaccine, the effect of three injections is better than that of two injections, and the neutralizing antibody titer produced is higher, so the three injection method is adopted.

3. Reason 3: Higher efficiency

Anhui Zhifei COVID-19 vaccine is a recombinant protein vaccine. The safety of this vaccine is relatively high. It is also very efficient and efficient to vaccinate three shots. Moreover, the validity period after this is relatively long, which can reach two years.

4. Reason 4: relatively strong immunity

After two doses of Anhui Zhifei COVID-19 vaccine, 83% of the vaccinated population can produce neutralizing antibodies. After 3 doses of vaccination, 97% of the vaccinated population can produce neutralizing antibodies.

III. Precautions for Anhui Zhifei COVID-19 Vaccination

1. People who are not allowed to receive Anhui Zhifei COVID-19 Vaccination

(1.1) People who are known to be allergic to vaccine ingredients, including excipients, are not recommended to be vaccinated;

(1.2) Vaccination is not recommended for individuals with acute diseases, severe chronic diseases, acute exacerbations of chronic diseases, and fever;

(1.3) Pregnant women;

(1.4) Individuals with uncontrolled epilepsy and other progressive neurological disorders are not eligible for vaccination.

2. Can Anhui Zhifei COVID-19 Vaccine be replaced with another COVID-19 Vaccine before the vaccination is completed?

It is not recommended to use another COVID-19 vaccine. If there are special circumstances such as the inability to continue supplying vaccines or vaccination of recipients in different locations, and it is not possible to complete vaccination with the same vaccine product, vaccines from other manufacturers of the same type can be used to complete vaccination. If the recombinant COVID-19 vaccine is used, the inactivated COVID-19 vaccine and adenovirus vector vaccine cannot be used to complete the follow-up vaccination.

To sum up, we can learn that the interval between three shots of Anhui Zhifei COVID-19 vaccine is recommended to be greater than or equal to 28 days, that is, about a month. If you take Anhui Zhifei COVID-19 vaccine on May 25, you need to take the second shot on the 25th of the next month, and the third shot on September 25. The purpose of Anhui Zhifei COVID-19 Big Three Vaccine is to strengthen the protection rate and produce higher antibodies.