Which is better, adapalene or tretinoin

Adapalene and tretinoin each have their own advantages, with tretinoin having a more significant effect when skin tolerance is good. Adapalene is more suitable for sensitive skin or beginners. Both are derivatives of vitamin A, but there are differences in their strength of action, irritability, and indications. Adapalene is a third-generation retinoid drug with strong stability and low photosensitivity, suitable for nighttime use. It reduces the formation of acne by regulating the differentiation of keratinocytes, and has a significant effect on closed mouth acne and mild inflammatory acne. The irritant effect is milder than traditional retinoids, and there may be slight flaking in the early stages, but it rarely causes erythema, making it suitable for long-term maintenance treatment. Attention should be paid to strict sun protection after use, and avoid overlapping with irritating skincare products such as alcohol and salicylic acid.

Retinoic acid, also known as all trans retinoic acid, is the first generation of potent keratolytic agents that can directly promote epidermal cell renewal. The improvement of stubborn acne, keratosis, and photoaging wrinkles is more significant, but it can easily cause dryness and peeling of the skin. Tolerance should be established starting from low concentrations, and other exfoliating products should be discontinued during use. Prohibited during pregnancy, easily decomposed and ineffective under sunlight. It is recommended to apply a thin layer after cleansing at night, and strengthen moisturizing and repairing barriers in the future.

Both drugs should be stored away from light and used under the guidance of a doctor. Initially, it is recommended to apply them at night the next day to test tolerance. During treatment, use oil-free moisturizer to relieve dryness and avoid using abrasive cleaning products. Acne patients need to adjust their diet structure synchronously, reduce the intake of high sugar and high-fat dairy products, and maintain a regular schedule to help control sebum secretion. If there is persistent redness, swelling, and pain, stop using it immediately and seek medical attention.