Whether the COVID-19 booster injection can be used with the vaccine that is not used for the first injection? Listen to the experts

Recently, the domestic epidemic has been fluctuating, with one area just ending and another appearing. Therefore, strengthening immunity is also very important now. At present, many provinces in China have also started to vaccinate the "booster shot" of COVID-19 vaccine. However, there are still many confusions about the booster shot. For people who received the first and second doses mixed, can the booster shot be mixed with a different vaccine than the first dose?

Can the "booster shot" vaccine be mixed with vaccines that do not require the first dose?

Shao Yiming said that whether it can be mixed with vaccines that do not require the first dose should be understood from both the scientific research and management levels. The mixed administration of vaccines at the scientific research level refers to vaccines with different technical routes. When used for other diseases, the actual effect is not worse than administering a third dose on the basis of the original vaccine. Sometimes, when combined well, the effect can be stronger. The mixed administration of vaccines at the management level requires sufficient safety and efficacy data for drug regulatory agencies to make decisions. Our research is advancing rapidly and the accumulated data will continue to grow. The current recommendation made by the National Medical Products Administration is to first administer the third dose of the same type of vaccine, but more data on different types of vaccines will be generated later, and new recommendations will be issued in the future. If the first and second doses are administered with different vaccines, the booster shot will choose to receive the same vaccine as the second dose. If there is no vaccine like the second dose, the same vaccine as the first dose will be administered. That is to say, for example, if you received the first dose from Beijing Biologics and the second dose from Beijing Kexing, then when receiving the booster shot, priority should be given to Beijing Kexing. However, if the place where you received the vaccine does not have Beijing Kexing, then you should receive the Beijing Biologics vaccine.

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