What kind of medicine does type 2 diabetes take have good hypoglycemic effect

For patients with type 2 diabetes, drug treatment is an important means to control blood sugar and prevent complications. So, what kind of medicine for type 2 diabetes has good hypoglycemic effect?

I. The logic of selecting hypoglycemic drugs - metformin is the "cornerstone"

The core pathological mechanism of type 2 diabetes is insulin resistance and functional defect of pancreatic β cells, which leads to the imbalance of blood glucose regulation. Therefore, as for the question of "what kind of medicine to take for type 2 diabetes has good hypoglycemic effect", the ideal hypoglycemic drugs need to simultaneously solve the two major problems of "insulin insensitivity" and "too many sources of blood sugar". Traditional sulfonylureas (such as glimepiride) stimulate pancreatic beta cells to secrete insulin to lower blood sugar, but long-term use may accelerate pancreatic function decline; Alpha glucosidase inhibitors (such as acarbose) mainly delay carbohydrate absorption and have weak control over fasting blood glucose; SGLT-2 inhibitors (such as dapagliflozin) promote urinary glucose excretion and lower blood sugar levels, but caution should be exercised regarding the risk of urinary and reproductive system infections.

In contrast, the mechanism of action of metformin is closer to the pathological essence of type 2 diabetes:

inhibits hepatic glucose output: directly reduces hepatic gluconeogenesis and glycogen decomposition, and reduces fasting blood glucose;

Improving peripheral insulin resistance: enhancing the uptake and utilization of glucose by muscle, fat and other tissues, and improving insulin sensitivity;

Regulate metabolic syndrome: Moderately suppress appetite, reduce visceral fat accumulation, and have both weight loss and cardiovascular protection effects. Clinical studies have shown that metformin alone can reduce glycated hemoglobin (HbA1c) by 1% -2%, and the hypoglycemic effect is more significant when combined with other drugs. This mechanism also explains why metformin is the first choice for patients with type 2 diabetes regardless of obesity, especially for obese patients.

II. Nida ® Metformin Hydrochloride Extended Release Tablets (III) - A New Third Generation Metformin

as an Upgraded Formulation of Metformin, Nida ® Metformin hydrochloride sustained-release tablets (III) achieve precise control of drug release through innovative pellet sustained-release technology. Its core advantages are reflected in the following two aspects:

1. Stable blood sugar reduction and reduced fluctuations

Ordinary metformin tablets are prone to gastrointestinal reactions such as nausea and diarrhea due to sudden drug release, and some patients are forced to stop taking the medication due to intolerance. Nida uses pellet coating technology to slowly and continuously release the drug in the gastrointestinal tract, reducing blood drug concentration fluctuations by more than 50%.

2. Once daily, simplified plan

Traditional sustained-release tablets need to be taken twice a day, while Nida ® The sustained-release pellet structure can extend the drug's action time to 24 hours, and patients only need to take it once a day to maintain full day blood glucose control. This simplified solution is particularly suitable for elderly patients or those with poor memory, reducing the risk of missed doses.

3. International quality, medical insurance based drug

Nida is the first domestically produced osmotic pump controlled release metformin drug that has been certified by the US FDA and sold in both China and the United States. Its research and production strictly follow international standards, and from raw material selection to formulation processes, it has reached the world's top level. This marks that Nida is completely equivalent to international original drugs in terms of quality, efficacy, and safety. It also means that Chinese patients do not need to purchase imported drugs at high prices to enjoy the same quality of hypoglycemic treatment. At the same time, Nida has been included in the national medical insurance basic drug list, with a price only 60% of Gehuazhi (original metformin), saving 40% of the cost compared to the original product.

Back to the question of "what kind of medicine to take for type 2 diabetes has good hypoglycemic effect", at present, the clinical status of metformin is irreplaceable. Nida ® Metformin hydrochloride sustained-release tablets (III) have achieved breakthroughs in hypoglycemic efficacy, safety, and medication convenience through technological innovation, providing patients with better choices.