Moderate supplementation of amino acids during fitness is usually safe, but excessive or improper use may cause side effects such as gastrointestinal discomfort, increased liver and kidney burden, and metabolic imbalance.
1. Gastrointestinal discomfort
Amino acid supplements may irritate the gastrointestinal mucosa and can cause nausea, bloating, or diarrhea when taken on an empty stomach. Some people are sensitive to specific amino acid components and may experience a burning sensation in the stomach. It is recommended to take with meals or choose sustained-release products. If there is persistent discomfort, discontinue use.
2. Liver and kidney burden
Long term excessive intake of amino acids can increase liver metabolic pressure and renal filtration load. Branched chain amino acids need to undergo liver and kidney transformation, and excessive amounts may induce elevated transaminases or urate deposition. Individuals with pre-existing liver and kidney diseases should avoid self supplementation and monitor relevant indicators.
3. Metabolic imbalance
Excess of a single amino acid can disrupt the balance of amino acids in the body and affect protein synthesis efficiency. For example, excessive lysine may antagonize arginine absorption, while excessive tryptophan may trigger serotonin fluctuations. It is recommended to supplement with natural foods to control the total daily intake.
4. Nutritional Dependence
Long term dependence on supplements may lead to a decrease in one's ability to synthesize amino acids and a reduction in the utilization of natural food protein. Sudden cessation of use may result in withdrawal symptoms such as fatigue and delayed muscle recovery. The dosage of supplements should be gradually reduced and transitioned to dietary intake as the main approach.
5. Allergy Risk
Some amino acids are extracted from whey or soy protein, and individuals with allergies may experience symptoms such as rash and respiratory irritation. Impurities remaining from hydrolysis processes may also trigger allergic reactions. Before use, the source of the ingredients should be confirmed, and small dose testing is required for the first attempt.
Fitness enthusiasts should prioritize natural high protein foods such as eggs, fish, and beans when supplementing with amino acids. The daily dosage of the supplement should not exceed 20 grams. Supplementing within 30 minutes after training has a better effect, avoid taking it with caffeine. If abnormal symptoms such as headache and darkened urine color occur, immediate cessation of use and medical examination of liver and kidney function should be sought. It is recommended to pause for one month every three months of use and regularly monitor blood and urine routine.
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