What are the reasons for low blood crystal permeability

Low blood crystal osmotic pressure may be caused by factors such as excessive water intake, malnutrition, abnormal kidney function, endocrine disorders, and drug effects.

1. Excessive water intake:

Drinking a large amount of water or intravenous infusion in a short period of time can cause blood dilution, a decrease in electrolyte concentration in plasma, and a decrease in crystal osmotic pressure. This situation is common after excessive consumption of low-permeability liquids, which may be accompanied by symptoms of water poisoning such as headache and nausea. It can usually recover on its own by limiting water intake.

2. Malnutrition: When long-term protein or sodium intake is insufficient, plasma albumin and electrolyte levels decrease, and crystal osmotic pressure decreases accordingly. Commonly seen in patients with extreme dieting and digestive and absorption disorders, it is necessary to adjust the diet structure to supplement high-quality protein and minerals.

3. Kidney diseases:

Chronic nephritis, nephrotic syndrome, and other kidney diseases may lead to excessive loss of urinary protein, while impaired reabsorption of renal tubules can cause abnormal excretion of electrolytes such as sodium and potassium. These patients often experience symptoms such as edema and fatigue, and require specialized renal function tests.

4. Hormonal abnormalities:

Syndrome of abnormal secretion of antidiuretic hormone (SIADH) can cause the kidneys to excessively reabsorb water, leading to dilutive hyponatremia. Hypothyroidism may also affect electrolyte metabolism and needs to be diagnosed through hormone level testing.

3. Drug factors:

Diuretics such as hydrochlorothiazide may accelerate sodium ion excretion, while certain antidepressants or chemotherapy drugs may interfere with the secretion of antidiuretic hormone. During the use of these medications, it is necessary to regularly monitor electrolytes and adjust medication plans under the guidance of a doctor if necessary.

It is necessary to maintain a balanced diet in daily life, with a daily sodium intake controlled at 5-6 grams, and prioritize high protein foods such as fish and lean meat. Avoid drinking more than 1000 milliliters of water at once after exercise, and those with chronic diseases should have their electrolytes rechecked every 3-6 months. If severe symptoms such as persistent fatigue, drowsiness, or convulsions occur, immediate medical attention should be sought to investigate critical conditions such as adrenal cortex dysfunction.