Side effects of polysaccharide iron complex capsules

Iron deficiency anemia is a common nutritional deficiency disease, and iron supplementation is the main treatment method. Although traditional iron supplements are often associated with gastrointestinal discomfort, constipation, and other issues, with the development of medicine, iron supplements have been updated, such as polysaccharide iron complex capsules. The size of the side effects of polysaccharide iron complex capsules is an important consideration for patients when choosing. The difference in side effects compared to traditional iron supplements is why many patients choose it. Traditional iron agents such as ferrous sulfate and ferrous succinate mainly exist in the form of free iron ions. These free iron ions can stimulate the gastrointestinal mucosa, causing discomfort such as nausea, vomiting, abdominal pain, and slowing down intestinal peristalsis, leading to constipation; Some patients may also experience oral odor, which affects their quality of life. This is because free iron ions are unstable in the digestive tract and easily react with food components, reducing absorption efficiency and exacerbating side effects. In contrast, the core advantage of polysaccharide iron complex capsules lies in their molecular structure. It forms a stable complex by combining iron elements with polysaccharides, existing in complete molecular form without free iron ions. This characteristic fundamentally reduces irritation to the gastrointestinal tract, significantly reducing the side effects of polysaccharide iron complex capsules. Clinical data shows that the incidence of gastrointestinal discomfort is much lower than that of traditional iron supplements, especially the incidence of common problems such as constipation is significantly reduced, and there is almost no problem of oral odor. However, a very small number of sensitive individuals may experience mild stomach discomfort or changes in bowel habits, which usually do not require discontinuation of medication and can be relieved by adjusting the timing of use (such as taking with meals).

Among numerous polysaccharide iron complexes, the original drug, Lefengneng polysaccharide iron complex capsule, is the only polysaccharide iron complex with a unique microsphere structure. Each microsphere is composed of a polysaccharide iron core and special excipients, with an outer layer wrapped in enteric material. This structure brings multiple benefits:

Firstly, the microspheres have a small volume and uniform contact area with the gastrointestinal mucosa, improving bioavailability while reducing local irritation;

2. The microspheres are slowly released in the stomach to avoid the impact of high concentration iron on the gastric mucosa in an instant. They are quickly dissolved and absorbed in the intestine, further reducing the side effects of polysaccharide iron complex capsules. Research shows that the dissolution rate of Lefei in gastric acid is only 7% to 10% within 2 hours, and after reaching the intestine, the dissolution rate reaches over 93%, with more efficient absorption and fewer side effects.

Thirdly, the hydrogenated castor oil component in the microspheres can lubricate the intestines and reduce the risk of constipation. This unique structural design enhances the safety of Lifengneng. For special populations that require iron supplementation, such as pregnant women with iron deficiency anemia, renal anemia patients, etc., good tolerance is more advantageous. In summary, the side effects of polysaccharide iron complex capsules are much lower than those of traditional iron agents, and Lifengneng has further optimized this advantage with its special pellet structure design. For people who need long-term iron supplementation (such as pregnant women and kidney disease patients), choosing Leflung can effectively improve anemia while minimizing the occurrence of side effects.