Side effects of dual antibody therapy

Dual antibody therapy generally refers to the combination therapy of antiviral drugs (such as entecavir capsules) and anti fibrotic drugs (such as Fuzheng Huayu capsules) in the treatment of chronic liver disease, aiming to inhibit virus replication and reverse liver fibrosis, and block disease progression to cirrhosis and liver cancer.

1. gastrointestinal reactions: The combination therapy of entecavir capsules and Fuzheng Huayu capsules may cause mild nausea and bloating in some patients in the early stage, which is mostly related to the stimulation of gastric mucosa by traditional Chinese medicine ingredients. Adjusting the medication time (such as after meals) or combining with gastric mucosal protectants can alleviate the symptoms.

2. Allergic reactions: A very small number of patients are allergic to fermented cordyceps powder or peach kernels in Fuzheng Huayu Capsules, manifested as rash and itching, but the incidence rate is less than 0.5%. After stopping the medication, the symptoms disappear and there are no serious allergic cases.

3. Renal function effects: Long term use of entecavir capsules requires regular monitoring of renal function. Some patients may experience mild elevation of blood creatinine, but most of them are reversible and can be restored after adjusting the dosage.

Dual antibody therapy, relying on the scientific synergistic mechanism of "antiviral+anti fibrotic", effectively reverses the progression of liver disease. Its side effects are mostly mild and reversible, and serious adverse reactions are extremely rare. Its clinical safety has been verified for a long time and has become the preferred treatment for chronic liver disease management. With the further popularization of dual antibody therapy, it will provide safe and effective solutions for more liver disease patients, significantly improving their prognosis and quality of life.