Is the third dose of COVID-19 vaccine safe in China? What's the difference between two and three doses of COVID-19 vaccine

Is COVID-19 Vaccine Safe in China

The whole process of research and development, testing, approval, marketing, storage, transportation and vaccination of vaccines in China has very strict management regulations, so that citizens can be assured of vaccination.

(1) Vaccine itself: At present, the COVID-19 vaccine used in China has carried out clinical research in accordance with the specifications, obtained the approval of the national drug supervision department, and can be used after strict identification.

(2) Vaccine storage and transportation: There is a complete vaccine cold chain system to ensure that storage and transportation are strictly carried out in accordance with regulations.

(3) Vaccination process: The vaccination unit and medical staff have undergone professional training and strict review, and are vaccinated according to standard operating procedures.

(4) Vaccine Flow Tracking: The country has established a national electronic vaccine traceability collaborative platform, where vaccines can be traced throughout the entire process, with traceable sources and destinations.

What is the difference between two and three doses of COVID-19 vaccine

The production process and technical route of the two vaccines are different.

The principle of COVID-19 inactivated vaccine is to use African green monkey kidney (Vero) cells for virus culture and amplification, inactivate the virus with β - propionolactone, retain antigen components to induce immune response of the body, and add aluminum hydroxide adjuvant to improve immunogenicity.

The principle of recombinant COVID-19 vaccine (CHO cell) is to recombine the receptor binding region (RBD) gene of COVID-19 S protein into the Chinese hamster ovary (CHO cell) gene, express it in vitro to form RBD dimer, and add aluminum hydroxide adjuvant to improve immunogenicity. Its technical principle is similar to that of the mature hepatitis B CHO cell vaccine.

Both vaccines have been approved by the national drug regulatory authorities and have good safety and immune efficacy, both of which can provide good protection. It is suggested that citizens do not need to deliberately wait for a certain vaccine, as long as their physical conditions are met, they can be safely vaccinated.