Double anti hepatitis B drugs

Double anti treatment of hepatitis B refers to the combined use of antiviral drugs and anti fibrosis drugs, which can comprehensively control the progress of hepatitis B through the dual mechanism of antiviral+anti fibrosis. This treatment mode can both inhibit virus replication and repair damaged liver tissue, significantly reducing the risk of cirrhosis and liver cancer.

1. Antiviral drugs: antiviral treatment is the cornerstone of hepatitis B treatment. At present, first-line drugs include entecavir, tenofovir fumarate (TDF) and propofol tenofovir (TAF). Entecavir can block the viral replication chain by inhibiting the activity of hepatitis B virus DNA polymerase. Long term use can maintain the viral load at a very low level, and the drug resistance rate is low, which is suitable for most patients; Tenofovir disoproxil fumarate is relatively safe for pregnant women, but regular monitoring of renal function is necessary; As an upgraded version, propafenone is less toxic to the kidneys and bones, making it more suitable for patients with renal insufficiency or elderly patients.

2. Anti fibrotic drugs: Anti fibrotic therapy reduces liver cell degeneration and necrosis, increases collagen degradation, prevents fibrosis progression, and reverses early damage. Common traditional Chinese patent medicines and simple preparations include Fuzheng Huayu Capsules and Anluo Huaxian Pills. The ingredients of Fuzheng Huayu Capsule include Danshen, fermented cordyceps powder, peach kernels, etc. It has the effects of promoting blood circulation, removing blood stasis, nourishing essence and liver. By reshaping the liver matrix structure, inhibiting the activation of stellate cells, and reducing liver cell damage, it exerts anti liver fibrosis effects. Pregnant women should avoid using it; Anluo Chemical Fiber Pill mainly consists of Rehmannia glutinosa and Panax notoginseng, which can cool the blood and promote blood circulation, making it suitable for patients with blood heat and stasis blood type.

The double antibody therapy for hepatitis B should strictly follow the principle of individualization. Patients should choose drug combinations under the guidance of doctors, and regularly review liver function, viral load and liver imaging indicators. At the same time, maintaining a light diet, quitting smoking and drinking, and avoiding excessive fatigue are necessary to maximize treatment effectiveness and protect liver health.