Does a lack of vitamin B2 cause insomnia

Lack of vitamin B2 generally does not directly lead to insomnia, but long-term deficiency may indirectly affect sleep quality. Vitamin B2 deficiency is mainly related to symptoms such as oral ulcers, skin inflammation, and eye fatigue. In severe cases, it may affect melatonin synthesis by interfering with tryptophan metabolism. Vitamin B2, as a coenzyme, participates in energy metabolism and antioxidant processes in the body. Its deficiency is usually manifested as mucosal damage symptoms such as angular stomatitis, glossitis, and seborrheic dermatitis. These discomforts may cause insomnia at night, but they are not the direct cause of insomnia. Clinical observations have found that individuals with vitamin B2 deficiency tend to experience daytime sleepiness rather than nighttime insomnia, which is related to the synergistic maintenance of nervous system function by the vitamin B family. When severe vitamin B2 deficiency persists for several months, it may interfere with the metabolic pathway of tryptophan conversion to serotonin. Due to serotonin being a precursor substance for synthesizing melatonin, this metabolic disorder may indirectly affect sleep rhythm regulation. This situation is more common in individuals with extreme malnutrition, and is less common in those with a balanced diet. Maintaining a balanced diet can prevent vitamin B2 deficiency, and it is recommended to consume foods rich in vitamin B2 such as animal liver, eggs, dairy products, etc. in moderation. If long-term insomnia occurs, common causes such as stress, anxiety, and caffeine intake should be investigated, and serum vitamin B2 levels should be tested if necessary. Improving sleep requires comprehensive adjustment of daily routines, and supplementing with vitamin B2 alone has limited effect on improving insomnia.