Will uric acid decrease after losing weight due to overweight

Overweight individuals typically experience a decrease in uric acid levels after weight loss. Losing weight can help improve metabolic disorders, reduce visceral fat accumulation, thereby reducing uric acid production and promoting excretion. But if extreme dieting or vigorous exercise is adopted to lose weight, it may lead to an increase in uric acid in the short term. Overweight or obesity is an important trigger for hyperuricemia, and excessive adipose tissue in the body can promote abnormal purine metabolism and increase uric acid synthesis. After scientific weight loss and reduction of fat content, insulin sensitivity is improved and the kidney's ability to excrete uric acid is enhanced. By combining dietary control with aerobic exercise, such as reducing daily intake of high purine foods and maintaining brisk walking, blood uric acid levels can gradually decrease. Some studies have shown that the decrease in uric acid levels can reach a certain level after weight loss. In rare cases, rapid weight loss may cause temporary elevation of uric acid levels. This is because the ketone bodies produced during fat breakdown competitively inhibit uric acid excretion, while vigorous exercise accelerates muscle breakdown metabolism and produces more purine substrates. People who adopt a ketogenic diet or excessively diet may experience this phenomenon. It is recommended to control the weight loss rate within a reasonable range every week to avoid daily water shortage or sudden increase in anaerobic exercise. During weight loss, it is recommended to maintain sufficient daily water intake, prioritize low-fat dairy products, eggs, fresh vegetables, and other low purine foods, and avoid animal organs and alcohol intake. Individuals with elevated uric acid levels should regularly monitor their indicators. If the levels continue to rise, they should seek medical attention promptly to rule out pathological factors such as gout or renal dysfunction. Scientific weight loss requires long-term adherence to a healthy lifestyle and cannot rely on short-term extreme measures.