What medicine should be taken to prevent abdominal weight gain during menopause

It is not recommended to take medication to control weight during menopause when gaining weight in the abdomen. Instead, dietary adjustments and exercise management should be prioritized. If accompanied by severe metabolic abnormalities, hormone regulating drugs, lipid-lowering drugs, insulin sensitizers, etc. can be used according to medical advice. Common drugs include estradiol valerate tablets, atorvastatin calcium tablets, metformin hydrochloride tablets, orlistat capsules, and levothyroxine sodium tablets.

1. Hormone regulating drug

Estradiol valerate tablets belong to estrogen supplements and are suitable for abnormal fat distribution caused by menopausal estrogen deficiency. This drug can improve the centripetal obesity caused by hormone level disorder, but the risk of thrombus should be strictly evaluated, and it is forbidden for patients with breast cancer and endometrial cancer. Similar drugs also include estrogen binding tablets, which need to be used in conjunction with the progesterone cycle.

2. Lipid lowering drugs

Atorvastatin calcium tablets can reduce low-density lipoprotein cholesterol and are suitable for abdominal obesity patients with menopausal complications and hyperlipidemia. This drug improves lipid metabolism by inhibiting liver cholesterol synthesis, which may lead to adverse reactions such as muscle soreness. Similar drugs such as simvastatin tablets require monitoring of liver function, while fenofibrate capsules are more suitable for individuals with elevated triglycerides.

III. Insulin sensitizer

Metformin hydrochloride tablets are used for abdominal obesity caused by menopausal insulin resistance, improving glucose metabolism by reducing hepatic glucose output. Common gastrointestinal reactions usually resolve within two weeks, and are contraindicated for those with severe renal insufficiency. Similar drugs such as pioglitazone may increase the risk of fractures and should be carefully evaluated for use.

4. Lipase inhibitor

Orlistat capsules reduce calorie intake by inhibiting intestinal fat absorption, making them suitable for obese individuals who have difficulty controlling their diet. During medication, there may be digestive symptoms such as oily stools, and a low-fat diet is necessary. Long term use should pay attention to the risk of fat soluble vitamin deficiency, and it is not recommended to extend the treatment course on one's own.

V. Thyroid Hormones

Levothyronine Sodium Tablets are only suitable for menopausal patients with hypothyroidism, and TSH levels need to be strictly monitored to adjust the dosage. Abuse may lead to arrhythmia and osteoporosis, and normal thyroid function individuals are prohibited from using it for weight loss. Whether subclinical hypothyroidism patients need medication should be evaluated by endocrinologists.

The accumulation of abdominal fat during menopause is mainly related to changes in lipid metabolism caused by a decrease in estrogen levels. It is recommended to ensure 30 minutes of aerobic exercise combined with impedance training daily, increase the intake of plant-based estrogens and high-quality protein such as soy products and deep-sea fish, and reduce refined carbohydrates and saturated fat. Regularly monitor indicators such as waist circumference, blood pressure, and blood sugar. If there is continuous weight gain or metabolic abnormalities, it is necessary to seek medical attention from a gynecology or endocrinology department in a timely manner to avoid health risks caused by self medication for weight loss. Maintaining a regular schedule and a positive mindset are equally important for alleviating menopausal symptoms.