What are the medicines for reducing oil and fat that do not harm the body

The drugs for reducing oil and fat should be used under the guidance of a doctor, and the relatively safe ones mainly include orlistat, metformin, liraglutide, acarbose, L-carnitine, etc. These drugs help with weight loss through different mechanisms, but it is important to strictly follow medical advice and avoid self medication.

1. Orlistat

Orlistat is a nationally approved over-the-counter weight-loss drug that reduces dietary fat absorption by inhibiting gastrointestinal lipase. Suitable for obese or overweight individuals, the common adverse reaction is fat diarrhea, and long-term use may affect the absorption of fat soluble vitamins. During medication, it is necessary to follow a low-fat diet and regularly monitor nutritional status.

2. Metformin

Metformin is originally a hypoglycemic drug, but it can assist in weight loss by improving insulin sensitivity. Especially suitable for obese patients with insulin resistance, which may cause gastrointestinal discomfort and be contraindicated for those with renal dysfunction. It should be noted that this medicine needs to be combined with dietary and exercise interventions in order to be effective.

3. Liraglutide

Liraglutide is a GLP-1 receptor agonist that can delay gastric emptying and increase satiety. Subcutaneous injection is required, which may cause nausea, vomiting and other reactions. It is contraindicated for patients with a history of medullary thyroid cancer. This medicine should be used strictly according to the dose escalation plan and should not be abruptly discontinued.

4. Acarbose

Acarbose indirectly reduces fat synthesis by inhibiting carbohydrate breakdown and slowing down sugar absorption. Common reactions such as bloating and flatulence should be taken together with the first staple food. Patients with chronic gastrointestinal diseases should use caution, and blood glucose changes should be monitored during medication.

5. L-carnitine

L-carnitine is an amino acid derivative involved in fat metabolism and can be used as an auxiliary supplement. However, the effect of simple supplementation is limited, and it needs to be combined with exercise to promote fatty acid oxidation. Excessive use may cause diarrhea, and pregnant and lactating women should use it under the guidance of a physician. The use of any weight loss medication should be based on dietary control and regular exercise. It is recommended to consume an appropriate amount of high-quality protein and dietary fiber daily, choose aerobic exercise such as brisk walking and swimming, and maintain at least 150 minutes of moderate intensity exercise per week. Regularly check liver and kidney function during medication, and seek medical attention immediately if serious adverse reactions occur. Weight loss should be gradual and avoid relying on drugs for rapid weight loss, which can lead to metabolic disorders. Special populations such as pregnant women, adolescents, and chronic disease patients need to carefully evaluate the risks of medication.