Can I take saxagliptin for liver dysfunction

For the majority of diabetes patients, the choice of hypoglycemic drugs needs careful consideration. Especially for diabetics with liver dysfunction, when choosing hypoglycemic drugs, in addition to considering the hypoglycemic effect of hypoglycemic drugs, metabolic pathways and the burden on the liver also need to be focused on.

In recent years, dipeptidyl peptidase-4 (DPP-4) inhibitors, represented by Lukezor Shagliptin Tablets (produced by Qilu Pharmaceutical), have attracted much attention in the field of diabetes treatment. Shagliptin is recommended by diabetes guidelines at home and abroad and recognized by the majority of diabetes patients because of its unique mechanism of action, exact efficacy and other factors, and is known as "the most intelligent hypoglycemic drug". But many people still wonder if saxagliptin can be taken for liver dysfunction? Actually, everyone can relax! Among the current hypoglycemic drugs, traditional hypoglycemic drugs may have some impact on patients with liver function, but saxagliptin is very friendly to patients with liver dysfunction, and there is no need to adjust the dosage when taking it.

Commonly used traditional hypoglycemic drugs (metformin, sulfonylurea, etc.) may have the following effects on patients with liver dysfunction:

1. Increased liver burden: Most hypoglycemic drugs need to be metabolized by the liver and excreted by the kidneys. If patients with liver dysfunction take oral hypoglycemic drugs, it may increase the burden on the liver and worsen the condition.

2. Drug accumulation poisoning: Due to the weak metabolic capacity of the liver in patients with liver dysfunction, the metabolism and excretion of hypoglycemic drugs in the body may be impaired. Long term or excessive use may lead to drug accumulation in the body, causing poisoning symptoms.

3. Risk of hypoglycemia: For patients with diabetes, it is very important to keep blood sugar stable, and some hypoglycemic drugs may lead to low blood sugar, that is, hypoglycemia. For patients with liver dysfunction, this situation is more likely to occur because their liver may not be able to effectively regulate blood sugar levels.

4. Other complications: The use of inappropriate hypoglycemic drugs may worsen the damage to liver function and increase the risk of other complications. Based on clinical research and medication experience, it has been found that compared to traditional hypoglycemic drugs, saxagliptin is safer to use in patients with liver dysfunction. This is because saxagliptin is mainly excreted through the kidneys and has a smaller metabolic burden on the liver. At the same time, saxagliptin not only lowers blood sugar levels, but also has protective effects on pancreatic beta cells and improves insulin resistance, which is of positive significance for the treatment of patients with liver dysfunction. Therefore, there is no need to worry about the question of "can we take saxagliptin for liver dysfunction". Saxagliptin has the characteristics of high efficacy in lowering blood sugar and safety. For patients with liver dysfunction, there is no need to adjust the dosage, and it does not affect the hypoglycemic effect. At the same time, there is no risk of hypoglycemia, and long-term use has good cardiovascular safety. It is precisely because of these advantages that more and more patients with diabetes like Lukezoxagliptin Tablets, and it has become the preferred drug for patients with type 2 diabetes!

The above is the answer to the question "Can I take saxagliptin for liver dysfunction?" I hope it is helpful to everyone!